Most of the numerical studies on radiofrequency ablation RFA utilize the Pennes bioheat equation to predict the temperature distribution and ablation volume post-treatment. However, in reality the propagation of thermal disturbance occurs usually at a finite speed with a delay ranging from 10 to 20 s in biological tissues. The present study investigates the differences between the Fourier and non-Fourier bioheat transfer models during RFA of breast tumor. A heterogeneous three-dimensional model of breast has been constructed based on the anatomical details available in the literature. The thermo-electric analysis has been performed using a finite element method FEM - based software by incorporating the coupled electric field distribution, the bioheat transfer equation, and the Arrhenius rate equation. The effect of temperature-dependent changes in electrical and thermal conductivities has been incorporated along with a non-linear model of blood perfusion.